Author

Christophe Le Tourneau

Institut Gustave RoussyORCID 0000-0001-9772-4686Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Maud T KamaliD· 2 shared Adeline DurandiD· 1 shared Agathe Kahn· 1 shared Amélie RoehrigiD· 1 shared Arnoldo FrigessiiD· 1 shared Baptiste SimoniD· 1 shared Céline VallotiD· 1 shared Claire BonneauiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

Maud T KamalORCID

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2 papers

Recent·Most cited

A single-nucleus multimodal framework reveals epigenomic priming of chemoresistant states in ovarian cancer

Yuna Landais, Juliette Bertorello, Marta Puerto, Agathe Kahn, Baptiste Simon, Amélie Roehrig, Adeline Durand, Marceau Quatredeniers, Constance Lamy, Enora Laas, Nicolas Pouget, Simon Dumas, Jean-Guillaume Féron, Virginie Fourchotte, Claire Bonneau, , Céline Vallot

This paper develops a single-nucleus multimodal framework to analyze transcriptional and histone modification landscapes in ovarian cancer, revealing epigenomic priming of chemoresistant states and its impact on treatment outcomes.

bioRxiv · Dec 8, 2025 · PreprintCancer Biology

External validation of prognostic and predictive gene signatures in head and neck cancer patients

Erlend I. F. Fossen, Mauricio Moreira-Soares, Marissa LeBlanc, Arnoldo Frigessi, Eivind J. Hovig, Laura Lopez-Perez, Estefanía Estévez-Priego, Liss Hernández, María Fernanda Cabrera-Umpiérrez, Giuseppe Fico, Ingeborg Tinhofer, Vanessa Sachse, Kathrin Scheckenbach, Christophe Le Tourneau, Maud T Kamal, , Stefano Cavalieri

The paper externally validates five gene signatures in head and neck cancer patients, showing their prognostic and predictive value for treatment outcomes.

medRxiv · Sep 24, 2024 · PreprintGenetic & Genomic Medicine