Cheng‐Yi Chen

This study identifies miRNA-124's role in cervical cancer by regulating CD45 alternative splicing and Th cell immune function through the GSK3-PSF-CD45 pathway.

The paper reports chromosome-level genome assemblies of two sea anemones and finds conserved chromosomal blocks across cnidarians and bilaterians, but loss of microsynteny in Hox and NK clusters.

This study shows that Hedgehog signaling is essential for PGC specification and endomesodermal patterning in Nematostella, suggesting zygotic induction rather than maternal factors.

This study investigates the role of canonical Wnt signaling in anterior regeneration of the annelid Aeolosoma viride, finding that Wnt pathway activation and inhibition affect regeneration outcomes.

This paper introduces an electroporation method for efficient shRNA delivery in Nematostella vectensis to enable rapid gene knockdown.

This study characterizes the regeneration process in Aeolosoma viride, showing high cell proliferation and blastema formation, and identifies cell proliferation as critical for regeneration.