Author

Aladdin Riad

University of PennsylvaniaORCID 0000-0002-0525-446XUnclaimed ORCID profile · follow to get notified of new preprints

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Neuroscience· 1

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Approach:experimental assay· 1

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Chenbo ZengiD· 1 shared Chi-Chang WengiD· 1 shared John Q. TrojanowskiiD· 1 shared Robert H. MachiD· 1 shared Virginia M.‐Y. LeeiD· 1 shared Zsofia Lengyel‐ZhandiD· 1 shared

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1 shared paperNeuroscience

Chenbo ZengORCID

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1 paper

Recent·Most cited

NeuroscienceMolecular NeurobiologyPeer-reviewedJun 23, 2020

The Sigma-2 Receptor/TMEM97, PGRMC1, and LDL Receptor complex are responsible for the cellular uptake of Aβ42 and its protein aggregates

Aladdin Riad, Zsofia Lengyel‐Zhand, Chenbo Zeng…·Robert H. Mach

This study identifies the Sigma-2 receptor/TMEM97, PGRMC1, and LDLR complex as a pathway for Aβ42 uptake in neurons, both with and without apoE, suggesting it as a potential therapeutic target for Alzheimer's disease.

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experimental assay

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