Molecular BiologyNature CommunicationsPeer-reviewed
Engineered transfer RNAs for suppression of premature termination codons
John D. Lueck, Jae Seok Yoon, Alfredo Perales‐Puchalt…·Christopher A. Ahern
This paper identifies engineered transfer RNAs (ACE-tRNA) that suppress premature termination codons in mammalian cells and mice, showing high suppression activity for common disease-causing nonsense codons.