PathologyFrontiers in MicrobiologyPeer-reviewed
Characterizing neuroinvasion and neuropathology of SARS-CoV-2 by using AC70 human ACE2 transgenic mice
Jason C. Hsu, Panatda Saenkham, Pinghan Huang…·Chien-Te Kent Tseng
This study investigates SARS-CoV-2 neuroinvasion via the trigeminal nerve in AC70 human ACE2 transgenic mice, finding it as an efficient route with altered neuronal function and gene expression but limited tissue pathology.
10 citations