Frédéric Lamoliatte

This study identifies PLK1-associated DNA repair factors and shows PLK1's role in mitotic DNA synthesis through specific interactions with SLX4 and RAD52.

The paper systematically identifies SLiM-binding interactions of USP family auxiliary domains using proteomic and biochemical methods, revealing functional redundancy and motif specificity.

This study identifies NRBP1 as an upstream activator of the WNK pathway by forming a multi-subunit complex with WNK1, SPAK, and TSC22D4 in response to osmotic stress.

The paper develops a tagless LysoIP method to isolate lysosomes from clinical samples and human cell lines, revealing glycerophosphodiesters as potential biomarkers for lysosomal storage disorders.

The paper shows that Zuo1, an Hsp40 cochaperone, is required for translational control and proteostasis maintenance in yeast under TORC1 inhibition.