Author

Anna Kłopot

Northwestern UniversityORCID 0000-0002-0556-3414Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:organoid / primary culture· 1 Assay:proteomics· 1

Frequent Co-Authors

Bethany E. Perez WhiteiD· 2 shared Irina V. BudunovaiD· 2 shared Patrick K. GrudzieniD· 2 shared Bo Shi· 1 shared Daria A. ChudakovaiD· 1 shared Dimitri TrubetskoyiD· 1 shared Dmitry Trubetskoy· 1 shared Lam C. TsoiiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Bethany E. Perez WhiteORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintApr 8, 2026

SKIN AS A POTENTIAL ENTRY POINT FOR SARS-COV-2

Dmitry Trubetskoy, Patrick K. Grudzien, Daria A. Chudakova…·Irina V. Budunova

This study shows that inflamed skin is more susceptible to SARS-CoV-2 infection, as cytokine-treated skin organoids and explants show increased ACE2 and TMPRSS2 expression and enhanced viral entry.

DOI 10.64898/2026.04.07.717019

humanorganoid / primary culture

𝕏 PostBluesky

ImmunologybioRxivPreprintNov 18, 2024

Activation of IL1A/IRAK1 axis and downstream proinflammatory signaling in healthy adult and neonatal African American skin

Dimitri Trubetskoy, Patrick K. Grudzien, Anna Kłopot…·Irina V. Budunova

The paper identifies increased activation of the IL1A/IRAK1 axis and downstream proinflammatory signaling in healthy African American skin compared to White Non-Hispanic skin, potentially contributing to higher risk of inflammatory skin diseases.

DOI 10.1101/2024.11.18.624144

humanproteomics

𝕏 PostBluesky