Reversing Glial Scar Back To Neural Tissue Through NeuroD1-Mediated Astrocyte-To-Neuron Conversion
Lei Zhang, Zhuofan Lei, Ziyuan Guo, Zifei Pei, Yu‐Chen Chen, Fengyu Zhang, Alice Cai, Yung Kin Mok, Grace Lee, Vishal Swaminathan, Fan Wang, Yuting Bai, Gong Chen
This study converts reactive astrocytes into neurons in mice, reducing glial scar and restoring neural tissue by rebalancing neuron-glia ratios.
bioRxiv · Feb 7, 2018 · PreprintNeuroscience