Author

Marie E. Egan

Yale UniversityORCID 0000-0002-0567-6048Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Adele S. RicciardiiD· 1 shared Alexandra S. Piotrowski-DaspitiD· 1 shared Anisha GuptaiD· 1 shared Anna Y. LynniD· 1 shared Cássia Lisboa BragaiD· 1 shared Christina BaroneiD· 1 shared David H. StitelmaniD· 1 shared Diane S. KrauseiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioengineering

Adele S. RicciardiORCID

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2 papers

Recent·Most cited

BioengineeringProceedings of the National Academy of SciencesPeer-reviewedJun 10, 2025

Systemic in utero gene editing as a treatment for cystic fibrosis

Adele S. Ricciardi, Christina Barone, Rachael Putman…·Marie E. Egan

This study demonstrates systemic in utero gene editing using PNAs in nanoparticles to correct CFTR mutations in multiple organs of CF mice, showing sustained CFTR activity without off-target effects.

11 citations

mouseexperimental assay

ImmunologybioRxivPreprintAug 2, 2024

CHRONIC LUNG INFLAMMATION LEADS TO MYELOID SKEWING OF HEMATOPOIETIC STEM CELLS IN A CYSTIC FIBROSIS MOUSE MODEL

Cássia Lisboa Braga, Rubia Isler Mancuso, Evrett N. Thompson…·Emanuela M. Bruscia

This study shows chronic lung inflammation in a CF mouse model increases myeloid bias in hematopoietic stem cells, which persists even after inflammation resolves.

DOI 10.1101/2024.08.02.606400

mouseflow cytometry