Author

Rachel R. Ogorzalek Loo

University of California, Los AngelesORCID 0000-0002-0580-2833Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Joseph A. LooiD· 2 shared Benjamin M. EllingsoniD· 1 shared Carolina Salas· 1 shared David S EisenbergiD· 1 shared Dennis W. DicksoniD· 1 shared Gerry ShawiD· 1 shared Hayden Zhao· 1 shared Ina B. WanneriD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Joseph A. LooORCID

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2 papers

Recent·Most cited

GFAP Degradation in TBI: Linking Novel Modified Products to Astrocyte Pathology and Patient Outcome

Ina B. Wanner, Julia Halford, Jonathan Lopez, Sean Shen, Yu Chen, Hayden Zhao, Carolina Salas, Rachel R. Ogorzalek Loo, Steven A. Robicsek, Benjamin M. Ellingson, JEFFREY A. GORNBEIN, Timothy E. Van Meter, Gerry Shaw, Joseph A. Loo, Paul M Vespa

This study identifies novel GFAP breakdown products and modifications in TBI patients, linking them to astrocyte pathology and clinical outcomes.

Acta Neuropathologica Communications · Apr 24, 2026Peer-reviewedNeuroscience

Amyloid fibrils in frontotemporal lobar degeneration with TDP-43 inclusions are composed of TMEM106B, rather than TDP-43

Yi Xiao Jiang, Qin Cao, Michael R. Sawaya, Romany N. N. Abskharon, Peng Ge, Michael A. Deture, Dennis W. Dickson, Janine Y. Fu, Rachel R. Ogorzalek Loo, Joseph A. Loo, David S Eisenberg

The paper identifies TMEM106B, not TDP-43, as the protein composing amyloid fibrils in FTLD-TDP using cryo-EM.

bioRxiv · Jan 31, 2022 · PreprintMolecular Biology