Bo Chen

This study shows cancer cells adapt to acidic tumor environments through sphingolipid metabolic plasticity, revealing that targeting metabolic flexibility, not individual pathways, may be more effective.

This study identifies novel GFAP breakdown products and modifications in TBI patients, linking them to astrocyte pathology and clinical outcomes.

This paper combines MicroED and native mass spectrometry to determine structures of enzyme-inhibitor complexes and identify high-affinity ligands from crude samples.

This study evaluates sphingolipid detection by MALDI-MSI, identifies optimal protocols, and reports artifacts from fragmentation in different ion modes.