Cancer BiologyCell Death and DiseasePeer-reviewed
HOOK2 downregulation compromises the tumorigenic and stemness properties of ovarian cancer cells by increasing endoplasmic reticulum stress
Elisa Suárez-Martínez, Asunción Espinosa-Sánchez, Sander R. Piersma…·Amancio Carnero
This study shows that reducing HOOK2 levels in ovarian cancer cells decreases tumor growth, migration, and stemness by increasing endoplasmic reticulum stress and cell death.
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