Author

Irene V. Bijnsdorp

Amsterdam University Medical CentersORCID 0000-0002-4261-3820Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:database / resource· 1 Assay:proteomics· 1

Frequent Co-Authors

Connie R. JiméneziD· 2 shared Sander R. PiersmaiD· 2 shared Thang V. PhamiD· 2 shared Amancio CarneroiD· 1 shared Anna WojtuszkiewicziD· 1 shared Asunción Espinosa-SáncheziD· 1 shared Bo WangiD· 1 shared Chantal ScheepbouweriD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

Connie R. JiménezORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

HOOK2 downregulation compromises the tumorigenic and stemness properties of ovarian cancer cells by increasing endoplasmic reticulum stress

Elisa Suárez-Martínez, Asunción Espinosa-Sánchez, Sander R. Piersma, Thang V. Pham, Irene V. Bijnsdorp, Connie R. Jiménez, Amancio Carnero

This study shows that reducing HOOK2 levels in ovarian cancer cells decreases tumor growth, migration, and stemness by increasing endoplasmic reticulum stress and cell death.

Cell Death and Disease · Apr 24, 2026Peer-reviewedCancer Biology

DPHL: A pan-human protein mass spectrometry library for robust biomarker discovery using Data-Independent Acquisition and Parallel Reaction Monitoring

Tiansheng Zhu, Yi Zhu, Yue Xuan, Huanhuan Gao, Xue Cai, Sander R. Piersma, Thang V. Pham, Tim Schelfhorst, Richard R. de Haas, Irene V. Bijnsdorp, Rui Sun, Liang Yue, Guan Ruan, Qiushi Zhang, Mo Hu, , Tiannan Guo

The paper introduces DPHL, a pan-human protein mass spectrometry library built using DIA and PRM, and demonstrates its utility in identifying differentially expressed proteins in prostate cancer and DLBCL.

Genomics Proteomics & Bioinformatics · Apr 1, 2020Peer-reviewedBioinformatics