Author

Javier Sastre Toraño

Utrecht UniversityORCID 0000-0002-0607-1892Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metagenomics· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Geert‐Jan BoonsiD· 2 shared André C. KnulstiD· 1 shared Anna M. EhlersiD· 1 shared Arthur E. H. BentlageiD· 1 shared Bernd StahliD· 1 shared Christian Klein· 1 shared Gaël M. VosiD· 1 shared Gerlof P. Bosman· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

Geert‐Jan BoonsORCID

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2 papers

Recent·Most cited

Asymmetrical Glyco-Engineering of Monoclonal Antibodies Provides Insights into α-Gal Immunogenicity

Gerlof P. Bosman, Anna M. Ehlers, Thomas Buckley, Justyna M. Dobruchowska, Javier Sastre Toraño, Arthur E. H. Bentlage, André C. Knulst, Gestur Vidarsson, Geert‐Jan Boons

This paper develops an enzymatic platform to synthesize diverse mAb glycoforms and uses them to study α-Gal immunogenicity and FcγR binding.

bioRxiv · Oct 27, 2026 · PreprintBiochemistry

De novo sequencing of complex glycans by ion mobility-mass spectrometry using a self-expanding reference database

Javier Sastre Toraño, Julia C. C. Vreugdenhil, Gaël M. Vos, Kevin C. Hooijschuur, Shannon Vogelaar, Christian Klein, John C. Fjeldsted, Bernd Stahl, Geert‐Jan Boons

This paper introduces a de novo sequencing method using ion mobility-mass spectrometry to identify isomeric glycans by building a self-expanding reference database from biological samples.

Nature Communications · Dec 13, 2025Peer-reviewedBiochemistry