NeurosciencebioRxivPreprint
Peripheral metabolic dysfunction drives sleep disruption in TDP-43 proteinopathy
Anyara Rodriguez, Jenny Luong, Samuel J. Belfer…·Matthew S. Kayser
This study shows that peripheral metabolic dysfunction, not just neuronal loss, causes sleep disruption in TDP-43 proteinopathy by identifying SIK3 as a key regulator.
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