Substitution spectrum and selection at G-quadruplexes in great ape telomere-to-telomere genomes
Xinru Zhang, Saswat K. Mohanty, Francesca Chiaromonte, Kateryna D. Makova
This study analyzes substitution patterns and selection at G-quadruplexes in great ape genomes, finding stronger purifying selection on stems than loops, especially in regulatory regions.
Genome Biology and Evolution · Feb 21, 2026Peer-reviewedEvolutionary Biology