Saswat K. Mohanty

460 haplotypes from 230 genomes, selected to maximize common-variant coverage, capture 99.43% of All of Us common small variants and halve structurally unreliable regions and base errors versus HPRC1.

The paper analyzes G-quadruplexes across the human pangenome, finding that they show distinct selection patterns and influence gene expression.

The paper benchmarks transcript classifiers to identify ambiguous mRNA-lncRNA classifications by analyzing uncertainty and feature contributions.

This study analyzes substitution patterns and selection at G-quadruplexes in great ape genomes, finding stronger purifying selection on stems than loops, especially in regulatory regions.

The paper analyzes single-stranded DNA (ssDNA) formation in human and non-human ape telomere-to-telomere genomes to identify non-B DNA structures and their functional roles.

The paper analyzes G-quadruplexes in T2T genomes of great apes, finding shared and species-specific G4s, their methylation patterns, and their potential role in gene regulation and adaptation.

The paper presents haplotype-resolved genomes of six ape species with high accuracy and provides comparative analyses to study evolutionary diversity and gene family evolution.