Chromatin tethering to the nuclear envelope enhances its accessibility to RNAPII and promotes chromatin asymmetric organization
Dana Lorber, Ido Azuri, Amit Kumar, Ron Rotkopf, Samuel A. Safran, Talila Volk
The paper shows that chromatin tethering to the nuclear envelope prevents clustering and enhances RNAPII accessibility, promoting asymmetric chromatin organization in Drosophila muscle nuclei.
bioRxiv · Mar 18, 2026 · PreprintMolecular Biology