Author
GenentechORCID 0000-0002-0637-4092Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Meghan M. Capeling, Bob Chen, Kazeera Aliar…·Michelle B. Chen
The paper builds a dictionary of human intestinal organoid responses to 81 secreted niche factors using scRNA-seq, mapping perturbations and identifying cell type-specific pathways in an IBD context.
Simone M. Haag, Shiqi Xie, Céline Eidenschenk…·Aditya Murthy
The paper identifies regulators of inflammatory macrophage states and shows that TNF mRNA m6A modification controls its stability and contributes to disease.
Shadi Toghi Eshghi, John Mark B. Gubatan, Parisa Mazrooei…·Jacqueline McBride
The paper identifies treatment resistance in ulcerative colitis linked to residual neutrophil subsets and inflammatory fibroblasts using single-cell analysis of biopsy data.