Emma Nyberg

Neuronal age drives β-sheet accumulation and, together with ApoE4, enhances synaptic Aβ localization in APPNL-F neurons

The paper shows that neuronal age and ApoE4 genotype increase synaptic Aβ accumulation and alter its structural form in APPNL-F neurons.

Apolipoprotein E intersects with amyloid-β within neurons

The paper shows that ApoE4 increases Aβ42 levels in neurons and demonstrates intracellular intersection of ApoE with APP/Aβ in AD transgenic neurons.