Jovan S. Brockett

The paper shows that DREAM and MEC NuRD complexes reinforce SPR-5/MET-2 maternal reprogramming to prevent germline gene expression in somatic tissues and developmental delay in C. elegans.

This study identifies a mechanism by which Centrocortin mRNA is co-translationally localized to centrosomes via dynein, microtubules, and a conserved dynein-binding motif.

The paper shows that in C. elegans, the balance between histone methylation systems MES-4 and SPR-5; MET-2 is essential for distinguishing germline from soma and preventing developmental delay.