Juvenile social isolation induces gene expression alterations and histone modification dysregulations in nucleus accumbens (NAc) neurons of female mice
Junpeng You, Akira Uematsu, Asuka Joji-Nishino…·Yusuke Kishi
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Human Informatics and Interaction Research InstituteORCID 0000-0002-0679-2649Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
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Junpeng You, Akira Uematsu, Asuka Joji-Nishino…·Yusuke Kishi
Aika Saito, Hiroyoshi Ogishima, Asuka Joji-Nishino…·Akira Uematsu
The paper identifies a neural mechanism in the ventral hippocampus that stabilizes aversive beliefs during extinction learning by suppressing adaptive behavioral changes.
Li-Feng Yeh, Takaaki Ozawa, Akira Uematsu…·Joshua P. Johansen
The paper identifies a brainstem circuit that transmits both sensory and motor information from aversive experiences to the amygdala, enhancing defensive behaviors and emotional memory formation.
Yusuke Kasuga, Xiao-Wei Gu, Tomoya Ohnuki…·Joshua P. Johansen
The paper introduces a technique called PINCER to study the functional input-output organization of neurons in neural circuits, demonstrating its application in the amygdala to reveal aversive memory-related cell types.
Mayumi Watanabe, Akira Uematsu, Joshua P. Johansen
This study shows that distinct subregions of the medial prefrontal cortex bidirectionally regulate emotional memory extinction through their influence on the locus coeruleus-noradrenaline system.
Michael A. Kelberman, Ellen M. Rodberg, Brandon R. Munn…·Nelson K. B. Totah
This study analyzes LC neuron firing patterns across species and biological factors, revealing diverse activity patterns and subregions enriched for specific factors and disease models.
Jessica Natali Sulkes Cuevas, Mayumi Watanabe, Akira Uematsu, Joshua P. Johansen
The paper maps afferent inputs to two functionally distinct noradrenaline cell types in the locus coeruleus and identifies sex-specific differences in their connectivity.