Yusuke Kishi

This study identifies NOTCH2NL as a human-specific gene promoting astrocyte proliferation and gliogenesis through expansion of glial progenitor states.

The paper identifies sex-biased transcriptome changes in Pax6 haploinsufficient mouse cortices and highlights Pbdc1 as a candidate regulator of sex-dependent corticogenesis.

This study identifies age-related transcriptomic and epigenetic changes in mouse hippocampus, highlighting cell-type-specific alterations in chromatin accessibility and gene regulation.

The paper identifies common and dataset-specific age-associated microglia populations across mouse and human datasets using integrative single-cell transcriptomic analysis.

The paper tracks chromatin accessibility changes in mouse embryonic deep-layer excitatory neurons during differentiation using RNA-seq and DNase-seq.

The paper shows neuronal migration in developing brains causes DNA damage through mechanostress, which is repaired normally but can lead to disease if unresolved.

The paper shows that species-specific differences in cortical excitatory neuron subtypes arise from non-uniform scaling of neurogenesis timing, regulated by Wnt signaling in rats.

This study shows that LPLAT11/MBOAT7 is essential for arachidonic acid incorporation into phosphatidylinositol, maintaining radial glial cell integrity and preventing cortical atrophy in developing neocortex.

This study shows neuronal micronuclei influence microglial states by altering their morphology and transcriptome during postnatal development.

The paper compares magnetic beads for CUT&Tag, finding that MyOne-T1 beads improve sensitivity due to better suspendability.

This study shows that Ring1, a Polycomb group protein, regulates ventral identity in the mouse telencephalon by suppressing BMP and Wnt signaling to allow Shh expression.

This study introduces a simple in utero injection method to introduce gene expression vectors into endo- and ectodermal cells of mouse embryos before neural tube closure, enabling tissue-specific labeling and analysis of gene function.