StrainOptimizer empowers rational cell factory design through multi-scale metabolic models with expression and proteome constraints
Haoyu Wang, Mengyao Zhang, Chengyu Zhang, Siwei He, Wenxing Liao, Rongpeng Zhu, Yongjin J. Zhou, Hongzhong Lu
StrainOptimizer improves microbial cell factory design by integrating multi-scale metabolic models with expression and proteome constraints, achieving higher bioproduction in yeast.
bioRxiv · Nov 3, 2025 · PreprintBioengineering