Author

Sarah Sabatinos

Toronto Metropolitan UniversityORCID 0000-0002-0685-7668Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:yeast· 3 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:genome assembly· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Essam Karam· 2 shared Mohammed Ayan Chhipa· 2 shared Ali MazalekiD· 1 shared Asiya Ahmed· 1 shared Jeffrey FillinghamiD· 1 shared Kazeera AliariD· 1 shared Kerenza Cheng· 1 shared Nairy Khodabshakian· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersGenetics

Essam Karam

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3 papers

Recent·Most cited

Modelling DNA replication fork stability and collapse using chromatin fiber analysis and the R-ODD-BLOBS program

Kerenza Cheng, Kazeera Aliar, Roozbeh Manshaei, Susan L. Forsburg, Ali Mazalek, Sarah Sabatinos

The paper models DNA replication fork stability using chromatin fiber analysis and the R-ODD-BLOBS program, showing changes in fork length and protein localization in different genetic backgrounds.

Computational and Structural Biotechnology Journal · Mar 1, 2026Peer-reviewedCell Biology

Fission yeast histone chaperone Rtt106 regulates histone levels, prevents early division, and promotes genome stability

Samantha A Sanayhie, Victoria A Da Pra, Nairy Khodabshakian, Essam Karam, Mohammed Ayan Chhipa, Seerat Kang, Asiya Ahmed, Jeffrey Fillingham, Sarah Sabatinos

bioRxiv · Nov 1, 2025 · PreprintGenetics

Checkpoint-dependent sensitivities to nucleoside analogues uncover specific patterns of genomic instability

Zainab Burhanuddin Kagalwala, Mohammed Ayan Chhipa, Zohreh Kianfard, Essam Karam, Sirasie P. Magalage, Sarah Sabatinos

This study tests the effects of nucleoside analogues on fission yeast with DNA replication checkpoint mutations, revealing sensitivity patterns and potential clinical implications.

Current Issues in Molecular Biology · Sep 12, 2025Peer-reviewedCell Biology