Cancer BiologybioRxivPreprint
Sex and Alkyladenine DNA Glycosylase Expression are Key Susceptibility Factors for NDMA-induced Mutations, Toxicity, and Cancer
Jennifer E. Kay, Joshua J. Corrigan, Lindsay B. Volk…·Bevin P. Engelward
This study investigates sex differences in susceptibility to NDMA-induced mutations, toxicity, and cancer in mice, finding males are more prone to cancer while Aag overexpression increases toxicity, particularly in females.
3 citations