Author

Sinem Karaman

University of HelsinkiORCID 0000-0002-0719-1773Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Aleksandra ZhaivoroniD· 1 shared João S. PatrícioiD· 1 shared Lauren G. ZachariasiD· 1 shared Lipsa Rani PandaiD· 1 shared Madeleine H. LackmaniD· 1 shared Markus Innilä· 1 shared Nahid Akthar KhaniD· 1 shared Serena S OzturkiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Aleksandra ZhaivoronORCID

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1 paper

Recent·Most cited

Mitochondrial genome instability disrupts brown adipose tissue through pseudohypoxia-iron-NAD⁺ axis

Serena S Ozturk, Swagat Pradhan, Madeleine H. Lackman, Lipsa Rani Panda, Aleksandra Zhaivoron, Markus Innilä, João S. Patrício, Lauren G. Zacharias, Thomas P. Mathews, Sinem Karaman, Nahid Akthar Khan

This study identifies a pseudohypoxia-iron-NAD+ axis as a key driver of brown adipose tissue dysfunction in mitochondrial disease using a mouse model.

bioRxiv · Aug 31, 2026 · PreprintMolecular Biology