Author

Giovanna Scapin

NanoImaging ServicesORCID 0000-0002-0724-2286Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Angela M. PhillipsiD· 1 shared Anthony KhalifehiD· 1 shared Claudio CatalanoiD· 1 shared Cole R Tharp· 1 shared Gyunghoon KangiD· 1 shared Ruimin Huang· 1 shared Sam Ghaffari-KashaniiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperEvolutionary Biology

Angela M. PhillipsORCID

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1 paper

Recent·Most cited

Biophysical trade-offs in antibody evolution are resolved by conformation-mediated epistasis

Cole R Tharp, Claudio Catalano, Anthony Khalifeh, Sam Ghaffari-Kashani, Ruimin Huang, Gyunghoon Kang, Giovanna Scapin, Angela M. Phillips

This study quantifies biophysical trade-offs in antibody evolution by analyzing surface expression, affinity, and self-reactivity across 213 evolutionary intermediates of a SARS-CoV-2 antibody lineage.

bioRxiv · Mar 17, 2026 · PreprintEvolutionary Biology