Claudio Catalano

This study quantifies biophysical trade-offs in antibody evolution by analyzing surface expression, affinity, and self-reactivity across 213 evolutionary intermediates of a SARS-CoV-2 antibody lineage.

This study reveals the structural basis of RecA-LexA interaction in Pseudomonas aeruginosa, showing how RecA triggers LexA cleavage and inactivation, which is critical for the SOS response.

The paper reports cryoEM structures of human serum albumin with and without ligands, demonstrating the feasibility of sub-4 Å resolution mapping for proteins using standard workflows.