Author

Angela M. Phillips

Harvard UniversityORCID 0000-0002-9806-7574Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1 Organism:yeast· 1

Frequent Co-Authors

Alex N. Nguyen BaiD· 1 shared Alief MoulanaiD· 1 shared Anthony KhalifehiD· 1 shared Arnaud N’GuessaniD· 1 shared Artur Rego‐CostaiD· 1 shared Caroline Holmes· 1 shared Cecilia TrivelliniD· 1 shared Christopher W. BakerleeiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperEvolutionary Biology

Alex N. Nguyen BaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Biophysical trade-offs in antibody evolution are resolved by conformation-mediated epistasis

Cole R Tharp, Claudio Catalano, Anthony Khalifeh, Sam Ghaffari-Kashani, Ruimin Huang, Gyunghoon Kang, Giovanna Scapin, Angela M. Phillips

This study quantifies biophysical trade-offs in antibody evolution by analyzing surface expression, affinity, and self-reactivity across 213 evolutionary intermediates of a SARS-CoV-2 antibody lineage.

bioRxiv · Mar 17, 2026 · PreprintEvolutionary Biology

Parallel but distinct adaptive routes in the budding and fission yeasts after 10,000 generations of experimental evolution

Arnaud N’Guessan, Vivian Wang, Christopher W. Bakerlee, Jenya Belousova, Greta Brenna, Megan E. Dillingham, Thomas Dupic, Shreyas Gopalakrishnan, Juhee Goyal, Misha Gupta, Caroline Holmes, Parris T. Humphrey, Tanush Jagdish, Elizabeth R. Jerison, Milo S. Johnson, , Alex N. Nguyen Ba

This study compares adaptive routes in two yeast species after 10,000 generations, finding parallel but distinct molecular mechanisms of adaptation.

Nature Ecology & Evolution · Mar 13, 2026Peer-reviewedEvolutionary Biology