Author

Anne Hoorens

Ghent University HospitalORCID 0000-0002-0736-2034Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Alfredo Dueñas ReyiD· 1 shared Anja M. GeertsiD· 1 shared Anne‐Françoise RouxiD· 1 shared Anneleen HeldensiD· 1 shared Daria FijałkowskaiD· 1 shared David RosenkranziD· 1 shared Dorien ClarisseiD· 1 shared Elfride B. W. De BaereiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetics

Alfredo Dueñas ReyORCID

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2 papers

Recent·Most cited

PPARalpha-ERRalpha crosstalk mitigates metabolic dysfunction-associated steatotic liver disease progression

Milton Boaheng Antwi, Sander Lefere, Dorien Clarisse, Lisa L. Koorneef, Anneleen Heldens, Louis Onghena, Kylian Decroix, Daria Fijałkowska, Jonathan Thommis, Madeleine Hellemans, Anne Hoorens, Anja M. Geerts, Lindsey Devisscher, Karolien De Bosscher

This study shows that targeting PPAR and ERR receptors reduces liver fat, fibrosis, and inflammation in MASLD models, suggesting a new therapeutic strategy.

Metabolism · Dec 30, 2024Peer-reviewedPharmacology & Toxicology

CEP162 deficiency causes human retinal degeneration and reveals a dual role inciliogenesis and neurogenesis

Nafisa Nuzhat, Kristof Van Schil, Sandra Liakopoulos, Miriam Bauwens, Alfredo Dueñas Rey, Stephan Käseberg, Melanie Jäger, Jason R. Willer, Jennifer Winter, Hanh M. Truong, Núria Gruartmoner Roura, Mattias Van Heetvelde, Joachim Wolf, Robert Merget, Sabine Grasshoff‐Derr, , Hanno J. Bolz

The paper shows that CEP162 deficiency causes retinal degeneration by impairing ciliary function, while retaining a role in neurogenesis.

Journal of Clinical Investigation · Mar 2, 2023Peer-reviewedGenetics