Author

Kylian Decroix

Ghent UniversityORCID 0000-0002-0344-5668Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Lindsey DevisscheriD· 2 shared Anja M. GeertsiD· 1 shared Anne HoorensiD· 1 shared Anneleen HeldensiD· 1 shared Christophe AmpèiD· 1 shared Daria FijałkowskaiD· 1 shared Delphine BurggraeveiD· 1 shared Dorien ClarisseiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Lindsey DevisscherORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 19, 2026

Pharmacological inhibition of deubiquitinase UCH-L1 by LDN57444 sensitises hepatocellular carcinoma to sorafenib by reverting drug-induced adaptive responses

Elias Van De Vijver, Kylian Decroix, Delphine Burggraeve…·Marleen Van Troys

This paper shows that combining LDN57444 with low-dose sorafenib enhances anti-tumor effects in hepatocellular carcinoma by reversing drug-induced adaptive responses.

DOI 10.64898/2026.05.15.725527

humanbulk RNA-seq

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Pharmacology & ToxicologyMetabolismPeer-reviewedDec 30, 2024

PPARalpha-ERRalpha crosstalk mitigates metabolic dysfunction-associated steatotic liver disease progression

Milton Boaheng Antwi, Sander Lefere, Dorien Clarisse…·Karolien De Bosscher

This study shows that targeting PPAR and ERR receptors reduces liver fat, fibrosis, and inflammation in MASLD models, suggesting a new therapeutic strategy.

17 citationstop 3%

mousebulk RNA-seq

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