Author

Rui Peng

Peking UniversityORCID 0000-0002-0739-4749Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:deep learning· 3 Research Focus:cell type annotation· 2 Assay:scRNA-seq· 2 Research Focus:benchmarking· 1 Research Focus:clustering· 1 Research Focus:dimensionality reduction· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Jinzhuo WangiD· 2 shared Beidi Chen· 1 shared Bin MaiD· 1 shared Buyao Li· 1 shared Demin ZhouiD· 1 shared Enze Ye· 1 shared Hailong ZhaoiD· 1 shared He Sun· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioinformatics

Jinzhuo WangORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Biologically grounded cell profiling across microscopy modalities

Enze Ye, Xiaoxuan Wu, Rui Peng, Wenjia Hu, Xiangyou Li, Xuefei Zhang, Mengxiao Niu, Yaorong Guo, Xinlei Sheng, Jinzhuo Wang, Liangyi Chen, He Sun

The paper introduces MorphAgent, a biologically grounded AI framework for cell profiling across microscopy modalities, improving feature design and performance in drug screening and disease analysis.

bioRxiv · Sep 28, 2026 · PreprintBioinformatics

Cardiolipin-mimic lipid nanoparticles without antibody modification delivered senolytic in-vivo CAR-T therapy for inflamm-aging

Zihan Zhang, Bin Ma, Buyao Li, Zhiwei Li, Min Gao, Hailong Zhao, Rui Peng, Jiang‐Miao Hu, Yu Wang, Wei You, Xun Gui, Rui Wang, Xiaoqing Hu, Beidi Chen, Yuanjie Zhang, , Lei Miao

This study develops cardiolipin-mimic lipid nanoparticles for in vivo CAR-T therapy without antibody modification, treating liver fibrosis and rheumatoid arthritis via circular uPAR CAR mRNA.

Cell Reports Medicine · Jul 1, 2025Peer-reviewedBioengineering

CellProphet: Dissecting Virtual Cell Differentiation through AI-Powered Dynamic Gene Regulatory Network Inference

Rui Peng, Yuanxu Gao, Yihan Chen, Jinzhuo Wang

CellProphet infers dynamic gene regulatory networks using AI, outperforming existing methods in differentiation datasets and accurately predicting cell fate transitions in mouse models.

bioRxiv · Feb 5, 2025 · PreprintBioinformatics