Author

Zihan Zhang

Chinese Academy of Medical Sciences & Peking Union Medical College

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Ao Gu· 1 shared Beidi Chen· 1 shared Bin MaiD· 1 shared Buyao Li· 1 shared Demin ZhouiD· 1 shared Fabao Chen· 1 shared Fan XuiD· 1 shared Haijing Shi· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCancer Biology

Ao Gu

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Nab-paclitaxel fused with the de novo designed receptor binder exhibits enhanced tumor targeting and therapeutic efficacy

Yuanying Qian, Weikang Yan, Fan Xu, Yali Liu, Fabao Chen, Yue Lu, Zihan Zhang, Ao Gu, Ruobing Yu, Zhen Fang, Yang Yu, Maolan Li, Longxing Cao, Yingbin Liu, Yongning He

This paper modifies Nab-paclitaxel with receptor binders to improve tumor targeting and reduce toxicity, showing enhanced efficacy in cancer cells and xenograft models.

Journal of Controlled Release · Sep 15, 2026Peer-reviewedCancer Biology

Identification of a new ORF3a-E fusion subgenomic RNA of SARS-CoV-2 and its biological features in the infection process

Yifan Zhang, Huiwen Zheng, Jing Li, Xin Zhang, Jiali Li, Heng Li, Xin Zhao, Zihan Zhang, Yingyan Li, Keqi Chen, Shasha Peng, Ying Zhang, Haijing Shi, Longding Liu

The paper identifies a new SARS-CoV-2 subgenomic RNA, ORF3a-E-sgRNA, which enhances viral replication and immune evasion by promoting translation and host protein interactions.

Frontiers in Immunology · Aug 15, 2025Peer-reviewedMicrobiology

Cardiolipin-mimic lipid nanoparticles without antibody modification delivered senolytic in-vivo CAR-T therapy for inflamm-aging

Zihan Zhang, Bin Ma, Buyao Li, Zhiwei Li, Min Gao, Hailong Zhao, Rui Peng, Jiang‐Miao Hu, Yu Wang, Wei You, Xun Gui, Rui Wang, Xiaoqing Hu, Beidi Chen, Yuanjie Zhang, , Lei Miao

This study develops cardiolipin-mimic lipid nanoparticles for in vivo CAR-T therapy without antibody modification, treating liver fibrosis and rheumatoid arthritis via circular uPAR CAR mRNA.

Cell Reports Medicine · Jul 1, 2025Peer-reviewedBioengineering