Patient-Derived Synovium-on-a-Chip Recapitulates Disease and Treatment Response and Permits Study of Resistance
Ruiqi Chen, Theresa Wampler Muskardin, Fanghao Shi…·Weiqiang Chen
This paper develops a patient-derived synovium-on-a-chip model to study RA disease and treatment response, finding that it correlates with clinical outcomes and identifies ECM signaling as a resistance mechanism.