Antonion Korcari

Maladaptive inflammatory signaling in old mice impairs colonic regeneration by promoting a sustained fetal-like epithelial state

This study identifies how aging impairs colonic regeneration in mice by promoting a fetal-like epithelial state through sustained IFNγ signaling.

Increased Ca2+ signaling through CaV1.2 induces tendon hypertrophy with increased collagen fibrillogenesis and biomechanical properties

This study shows that increased CaV1.2 Ca2+ signaling in tendon fibroblasts leads to tendon hypertrophy, increased collagen fibrillogenesis, and improved biomechanical properties.