Induction of an alternative 5’ leader enhances translation of Inpp5e and resistance to oncolytic virus infection
Huy‐Dung Hoang, Tyson Ernst Graber, Jianjun Jia, Nasana Vaidya, Victoria Heather Gilchrist, Xiao Xiang, Wencheng Li, Kyle Northcote Cowan, Christos G. Gkogkas, Maritza Jaramillo, Seyed Mehdi Jafarnejad, Tommy Alain
The paper identifies an alternative 5' leader in Inpp5e mRNA that enhances translation and confers resistance to oncolytic virus infection in cancer cells.
Cell Reports · Dec 1, 2019Peer-reviewedMolecular Biology