Tyson Ernst Graber

Municipal Wastewater in Ottawa, Canada contains a reservoir of bacteriophages with clinically relevant Escherichia coli and Klebsiella pneumoniae Hosts

This study identifies and characterizes bacteriophages in Ottawa's municipal wastewater that can infect clinically relevant E. coli and K. pneumoniae strains, showing high similarity to European phages but with genetic divergence.

Urban wastewater contains a functional human antibody repertoire of mucosal origin

The paper identifies and characterizes a human antibody repertoire from wastewater, showing it can track immune correlates and aid in vaccine efficacy assessment.

Puromycin reveals a distinct conformation of neuronal ribosomes

The paper shows that puromycylated peptides remain in neuronal ribosomes in a hybrid state, revealing a distinct conformation and stalling mechanism in neurons.

Induction of an alternative 5’ leader enhances translation of Inpp5e and resistance to oncolytic virus infection

The paper identifies an alternative 5' leader in Inpp5e mRNA that enhances translation and confers resistance to oncolytic virus infection in cancer cells.