Author

Andrea Ameruoso

Rice UniversityORCID 0000-0002-0752-6975Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

James ChappelliD· 2 shared August O. StaubusiD· 1 shared Katherine Piper Cohen· 1 shared Kim Wai Mo· 1 shared Lauren GambilliD· 1 shared Maria Claudia Villegas KcamiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 9 mutual co-author links

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2 shared papersSynthetic Biology

James ChappellORCID

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2 papers

Recent·Most cited

A split ribozyme that links detection of a native RNA to orthogonal protein outputs

Lauren Gambill, August O. Staubus, Kim Wai Mo, Andrea Ameruoso, James Chappell

This paper introduces RENDR, a system that uses RNA to control protein outputs by splicing split ribozymes, demonstrating detection of antibiotic resistance in bacteria.

Nature Communications · Feb 1, 2023Peer-reviewedSynthetic Biology

Activating natural product synthesis using CRISPR interference and activation systems in Streptomyces

Andrea Ameruoso, Maria Claudia Villegas Kcam, Katherine Piper Cohen, James Chappell

This paper develops CRISPRi and CRISPRa systems in Streptomyces to activate silent biosynthetic gene clusters for antibiotic discovery.

Nucleic Acids Research · Jul 8, 2022Peer-reviewedSynthetic Biology