Author

Lucien Rufener

ORCID 0000-0002-0754-9923Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:imaging· 1 Organism:non-human primate· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Alexandre VernudachiiD· 1 shared Anouk Sarr· 1 shared Coralie Belgrano· 1 shared Hanna M. SahlströmiD· 1 shared Kristian H. Horsberg· 1 shared Laurent MouchiroudiD· 1 shared Marit Jørgensen BakkeiD· 1 shared Morgane BourgeoisiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperDevelopmental Biology

Alexandre VernudachiORCID

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2 papers

Recent·Most cited

AlphaFold-Multimer Modelling of Linked nAChR Subunits Challenges Concatemer Design Assumptions

Hanna M. Sahlström, Lucien Rufener, Kristian H. Horsberg, Anouk Sarr, Tor Einar Horsberg, Marit Jørgensen Bakke

The paper uses AlphaFold-Multimer to model nAChR subunit stoichiometry in Lepeophtheirus salmonis, challenging assumptions about concatemer design.

Scientific Reports · Apr 27, 2026Peer-reviewedBioinformatics

Unveiling mode of action of anthelmintics in Caenorhabditis elegans with SydLab™, an on-a-chip automated and high-content screening system.

Thomas B. Duguet, Coralie Belgrano, Morgane Bourgeois, Alexandre Vernudachi, Laurent Mouchiroud, Lucien Rufener

This study evaluates eight anthelmintic compounds in C. elegans using SydLab, identifying drug-specific phenotypes and modes of action through automated imaging and machine learning.

bioRxiv · May 15, 2025 · PreprintDevelopmental Biology