Unveiling mode of action of anthelmintics in Caenorhabditis elegans with SydLab™, an on-a-chip automated and high-content screening system.
Thomas B. Duguet, Coralie Belgrano, Morgane Bourgeois, Alexandre Vernudachi, Laurent Mouchiroud, Lucien Rufener
This study evaluates eight anthelmintic compounds in C. elegans using SydLab, identifying drug-specific phenotypes and modes of action through automated imaging and machine learning.
bioRxiv · May 15, 2025 · PreprintDevelopmental Biology