Systems BiologybioRxivPreprint
Proximity map for p53 unveils a strong link with PML Nuclear Bodies in HEK293 cells
Edith De Bruycker, Giel Vandemoortele, Delphine De Sutter…·Sven Eyckerman
The paper uses BioID proximity labeling to show p53 interacts with PML nuclear bodies and SUMOylation proteins in HEK293 cells, linking these interactions to differences in p53 transcriptional activity compared to HCT116 cells.
DOI 10.1101/2025.10.22.683840