Author

James J. Cameron

Tufts UniversityORCID 0000-0002-0772-0292Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

Tyler R. ColsoniD· 2 shared Xudong Joshua LiiD· 2 shared Alexander N. PoltorakiD· 1 shared Hayley I. MuendleiniD· 1 shared James H. KimiD· 1 shared Jamie L. LeiriaoiD· 1 shared Mei-An NolaniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

Tyler R. ColsonORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Dot1L licenses DNA demethylation to establish regulatory T cell identity

James J. Cameron, Tyler R. Colson, Xudong Joshua Li

This study identifies Dot1L-mediated H3K79 methylation as essential for Treg-specific DNA demethylation, which is critical for Treg identity and function.

bioRxiv · Jan 14, 2026 · PreprintImmunology

Regulatory T cells epigenetically reprogrammed from autoreactive effector T cells mitigate established autoimmunity

Tyler R. Colson, James J. Cameron, Hayley I. Muendlein, Mei-An Nolan, Jamie L. Leiriao, James H. Kim, Alexander N. Poltorak, Xudong Joshua Li

This study reprograms autoreactive effector T cells into stable regulatory T cells using epigenetic modification, showing improved efficacy in treating autoimmune neuroinflammation.

bioRxiv · Jul 24, 2025 · PreprintImmunology