Author

Bradley Priem

Johns Hopkins UniversityORCID 0009-0002-2849-6119Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:drug response / drug discovery· 2 Assay:metabolomics· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Michael J. BetenbaughiD· 3 shared Ana María Vega-LetteriD· 1 shared Andrew S PekosziD· 1 shared Anne RichelleiD· 1 shared Athanasios AntonakoudisiD· 1 shared Benjamin StrainiD· 1 shared Blaise Manga EnuhiD· 1 shared Camila A. OrellanaiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersBioengineering

Michael J. BetenbaughORCID

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3 papers

Recent·Most cited

BioengineeringJournal of Biological EngineeringPeer-reviewedApr 24, 2026

A continuous viral vaccine biomanufacturing platform utilizing multiple bioreactor configurations

Justin Sargunas, Bradley Priem, Dylan R. Carman…·Michael J. Betenbaugh

This paper presents a continuous biomanufacturing platform for virus-like particle vaccines using multiple bioreactor configurations, demonstrating stable production and scalability.

DOI 10.1186/s13036-026-00680-7

protein structurestatistical model

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Cancer BiologybioRxivPreprintJan 6, 2026

Drug-tolerant persister cells reallocate carbon sources to fuel antioxidant metabolism for survival

Melvin Li, Bradley Priem, Luke V. Loftus…·Sarah R. Amend

This study identifies metabolic shifts in drug-tolerant persister cells that support antioxidant metabolism, offering new targets to overcome therapy resistance.

DOI 10.64898/2026.01.05.697775

humanmetabolomics

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Systems BiologybioRxivPreprintApr 10, 2025

A community-consensus reconstruction of Chinese Hamster metabolism enables structural systems biology analyses to decipher metabolic rewiring in lactate-free CHO cells

Pablo Di Giusto, Dong‐Hyuk Choi, Athanasios Antonakoudis…·Nathan E. Lewis

The paper presents iCHO3K, a comprehensive metabolic model of Chinese Hamster cells, and uses it to analyze metabolic changes in lactate-free cells, identifying structural insights into metabolic rewiring.

3 citations

mousemetabolomics

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