Yoshimitsu Kakuta

This study shows how PSG2 antibody discriminates between sulfotyrosine and phosphotyrosine through a balance of direct interactions and desolvation effects.

The paper elucidates the hydrolysis mechanism of Family II inorganic pyrophosphatase using structural and computational methods, identifying a μ-oxo nucleophile as the rate-limiting step.

This study characterizes the crystal structure of a thermophilic family II inorganic pyrophosphatase from Thermodesulfobacterium commune, revealing structural features that confer thermal stability.