Ulla Sovio

Maternal immune gene expression trajectories and dynamic genetic regulation throughout pregnancy

This study tracks maternal immune gene expression and genetic regulation throughout pregnancy, revealing dynamic changes and genetic interactions linked to pregnancy complications.

Somatic mutations reveal widespread mosaicism and mutagenesis in human placentas

This study uses whole genome sequencing of placental biopsies to show that human placentas exhibit clonal expansions, copy number changes, and developmental bottlenecks similar to childhood cancer.

Genetic architecture of early childhood growth phenotypes gives insights into their link with later obesity

This study identifies genetic loci associated with early childhood growth phenotypes and links them to later adiposity traits, suggesting potential targets for obesity prevention.