Nicole M. Warrington

The paper tests associations between maternal KIR haplotypes and fetal HLA-C alleles with birth weight in a large sample, finding no significant interactions or replication of previous findings.

This study identifies age-varying genetic contributions to BMI using longitudinal data from the ALSPAC cohort, showing distinct genetic profiles in infancy versus later childhood and adolescence.

The paper investigates the interaction between FADS2 genotype and breastfeeding on various traits in the UK Biobank and finds no evidence of such an interaction.

The paper introduces a framework for time-varying GWAS to identify age-varying genetic effects on BMI across childhood, finding 28 genome-wide significant variants, including a novel one in DAOA.

DINGO improves locus discovery in GWAS of perinatal traits by combining maternal and fetal GWAS data through meta-analysis and novel statistical tests, identifying more genetic loci than separate analyses.

This paper uses Mendelian randomization to investigate the causal relationship between maternal serum urate and offspring birthweight, finding a weaker causal effect compared to observational studies.

This paper uses structural equation modelling to partition the genetic effects of classical HLA alleles on birth weight into maternal and fetal components using UK Biobank data.

The paper examines the effect of fetal genetic predispositions to metabolically favourable adult adiposity and BMI on birth weight and other anthropometric traits, finding stronger associations with birth weight for the adiposity alleles.

This study uses Mendelian Randomisation to show that maternal metabolically favourable adiposity is associated with lower offspring birth weight compared to general adiposity indexed by BMI.

The paper compares multivariate methods to estimate direct and indirect genetic effects on offspring phenotypes using GWAS summary data, finding Genomic SEM most accurate and identifying novel fertility loci.

This study uses Mendelian Randomization to assess the causal effect of maternal vitamin B12 and folate on offspring birthweight, finding a positive causal effect for folate but not for B12.

This paper estimates indirect parental genetic effects on offspring phenotypes using virtual parental genotypes derived from sibling and half-sibling pairs, demonstrating the feasibility of this approach with GWAS data.

This study identifies genetic effects on birth weight and their impact on cardio-metabolic traits, distinguishing fetal and maternal contributions.

This paper uses structural equation modeling to estimate maternal and fetal effects on birthweight using UK Biobank data, identifying SNPs with opposing effects.

This study identifies maternal genetic variants associated with offspring birth weight using GWAS and SEM, showing independent effects from fetal genetics.

This study investigates the genetic contributions to gestational weight gain, finding that maternal common variants explain about 20% of variability, while fetal variants have a minor role.

This study identifies genetic loci associated with early childhood growth phenotypes and links them to later adiposity traits, suggesting potential targets for obesity prevention.