Author

Sophie Hoffman

Wellcome Sanger InstituteORCID 0000-0003-2518-6422Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Adam M. PhillippyiD· 1 shared Ágnes OszláncziiD· 1 shared Andrea GuarracinoiD· 1 shared Carmen Sancho‐SerraiD· 1 shared Cecilia Icoresi-MazzeoiD· 1 shared Céleste E. CoheniD· 1 shared Christian Malte BeckeriD· 1 shared David S. JonesiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperGenomics

Adam M. PhillippyORCID

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3 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintSep 25, 2026

Maternal immune gene expression trajectories and dynamic genetic regulation throughout pregnancy

Sophie Hoffman, Katie L. Burnham, Emma Cook…·Emma E. Davenport

This study tracks maternal immune gene expression and genetic regulation throughout pregnancy, revealing dynamic changes and genetic interactions linked to pregnancy complications.

DOI 10.64898/2026.09.22.26363644

humanbulk RNA-seq

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GenomicsbioRxivPreprintSep 13, 2024

Epigenetic control and inheritance of rDNA arrays

Tamara Potapova, Paxton Kostos, Sean McKinney…·Jennifer L. Gerton

The paper investigates epigenetic regulation of rDNA arrays, showing DNA methylation controls their activity and inheritance across generations.

12 citations

humannon-human primate

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GenomicsNature GeneticsPeer-reviewedAug 28, 2024

An integrated single-cell reference atlas of the human endometrium

Magda Marečková, Luz García‐Alonso, Marie Moullet…·Roser Vento‐Tormo

The paper constructs a high-resolution single-cell reference atlas of the human endometrium, identifying cell types, states, and signaling networks, and links them to endometriosis.

182 citationstop 1%

humanscRNA-seq

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