The small GTPase Rab5 inhibits actin polymerization mediated by the Legionella pneumophila effector VipA
Joana Saraiva, Joana N. Bugalhão, Teresa Gil Carvalho, Zach Hensel, Álvaro H. Crevenna, L. Jaime Mota, Irina Saraiva Franco
This study identifies Rab5 as an interacting partner of the L. pneumophila effector VipA, showing that Rab5 binding inhibits VipA's ability to promote actin polymerization.
Medical Microbiology and Immunology · Apr 2, 2026Peer-reviewedMicrobiology