Author

Jack‐Christophe Cossec

InsermORCID 0000-0002-0836-1009Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Assay:Hi-C· 1

Frequent Co-Authors

Tatiana TraboulsiiD· 2 shared Agnès ThierryiD· 1 shared Andrey I. AristoviD· 1 shared Anne DejeaniD· 1 shared Charles Naim BaroudiD· 1 shared Clara DelahousseiD· 1 shared Marion Salmon-Legagneur· 1 shared Nadia Vertti‐QuinteroiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioengineering

Tatiana TraboulsiORCID

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2 papers

Recent·Most cited

Culture of pluripotent stem cells in microscale droplets modulates differentiation and tissue patterning towards organoids on chip

Nadia Vertti‐Quintero, Clara Delahousse, Andrey I. Aristov, Tatiana Traboulsi, Jack‐Christophe Cossec, Charles Naim Baroud, Sébastien Sart

This study shows that culturing pluripotent stem cells in microscale droplets promotes differentiation into three germ layers and organoid formation, with enhanced tissue patterning and self-organization.

Stem Cell Research & Therapy · Sep 26, 2025Peer-reviewedBioengineering

Z-DNA formation induces the totipotent-like state and primes Zscan4-dependent chromatin compartmentalization

Shireen Shajahan, Yann Loe-Mie, Marion Salmon-Legagneur, Tatiana Traboulsi, Agnès Thierry, Anne Dejean, Jack‐Christophe Cossec

The paper shows that Z-DNA formation promotes totipotent-like state and primes Zscan4-dependent chromatin compartmentalization during early mouse development.

bioRxiv · Mar 18, 2025 · PreprintCell Biology